
GU / Renal
NCLEX Clinical Study Booklet · 11 cards
Urinary Tract Infection.
InfectionWhat is Urinary Tract Infection?
- Infection of the urinary tract (usually the bladder = cystitis).
- More common in women (short urethra).
What are the Causes / Risk Factors?
- E. coli (most common)
- Catheterization
- Poor hygiene
- Urinary retention, sexual activity
What are the Symptoms?
- Dysuria (burning)
- Frequency, urgency
- Cloudy, foul-smelling urine
- Suprapubic pain
- Hematuria
- Elderly: confusion may be the only sign
How is it Diagnosed?
- Urinalysis (↑WBC, bacteria, nitrites)
- Urine culture
What is the Treatment?
- Antibiotics
- ↑fluids (2–3 L/day)
- Void frequently; wipe front to back
- Complete antibiotics; avoid irritants
NCLEX TipIn older adults, new confusion may be the only sign of a UTI. Teach wiping front-to-back and completing antibiotics.
Pyelonephritis.
InfectionWhat is Pyelonephritis?
- Infection of the kidney(s) — an upper UTI.
- Can cause scarring or sepsis.
What are the Causes / Risk Factors?
- Ascending UTI
- Obstruction, reflux
- Catheter, stones
What are the Symptoms?
- Flank / CVA tenderness
- High fever, chills
- N/V
- Dysuria, frequency
- Cloudy / bloody urine
How is it Diagnosed?
- Urinalysis & culture
- ↑WBC
- CT / ultrasound
What is the Treatment?
- Antibiotics (may be IV)
- ↑fluids
- Antipyretics, pain control
- Follow-up cultures; treat obstruction
NCLEX TipFlank pain + CVA tenderness + fever points to pyelonephritis (kidney), not just a bladder UTI.
Acute Kidney Injury.
EmergencyWhat is Acute Kidney Injury?
- Sudden decline in kidney function.
- Prerenal, intrarenal, or postrenal — often reversible.
What are the Causes / Risk Factors?
- Prerenal: hypovolemia, shock, HF
- Intrarenal: nephrotoxins, ATN
- Postrenal: obstruction (stones, BPH)
What are the Symptoms?
- ↓urine output (oliguria)
- ↑BUN / creatinine
- Fluid overload, edema
- Hyperkalemia
- Metabolic acidosis
- Confusion
How is it Diagnosed?
- ↑BUN/creatinine
- Electrolytes (↑K)
- Urinalysis
- Renal ultrasound
What is the Treatment?
- Treat cause; restore perfusion
- Fluid & electrolyte management
- Monitor I&O, daily weight
- Dialysis if severe; avoid nephrotoxins
NCLEX TipWatch for hyperkalemia in AKI — it can cause fatal dysrhythmias. Monitor I&O, daily weight, and potassium.
Chronic Kidney Disease.
ChronicWhat is Chronic Kidney Disease?
- Progressive, irreversible loss of kidney function.
- End stage = dialysis or transplant.
What are the Causes / Risk Factors?
- Diabetes (leading cause)
- Hypertension
- Glomerulonephritis
- Polycystic kidney disease
What are the Symptoms?
- ↑BUN/creatinine, ↓GFR
- Fluid overload, edema, HTN
- Hyperkalemia, metabolic acidosis
- Anemia (↓erythropoietin)
- Uremia (pruritus, nausea), bone disease
How is it Diagnosed?
- ↓GFR
- ↑BUN/creatinine
- Electrolytes, CBC, imaging
What is the Treatment?
- Restrict protein, sodium, potassium, phosphorus, fluids
- Phosphate binders, erythropoietin
- Manage BP & glucose
- Dialysis / transplant
NCLEX TipCKD diet: limit protein, sodium, potassium, phosphorus, and fluids. Treat anemia with erythropoietin.
Nephrotic Syndrome.
RenalWhat is Nephrotic Syndrome?
- Glomerular damage → massive protein loss in urine.
- Hallmarks: proteinuria, hypoalbuminemia, edema, hyperlipidemia.
What are the Causes / Risk Factors?
- Glomerular disease
- Diabetes
- Lupus
- Infections, drugs
What are the Symptoms?
- Massive proteinuria (frothy urine)
- Generalized edema (periorbital, ascites)
- Hypoalbuminemia
- Hyperlipidemia
- Weight gain
How is it Diagnosed?
- Urinalysis (heavy protein)
- ↓serum albumin
- ↑lipids
- Renal biopsy
What is the Treatment?
- Corticosteroids, immunosuppressants
- ACE inhibitors (reduce proteinuria)
- Diuretics, low-sodium diet
- Monitor edema, weight, infection risk
NCLEX TipNephrotic syndrome = massive proteinuria + edema + low albumin + high lipids. Watch for infection (loss of immunoglobulins).
Glomerulonephritis.
RenalWhat is Glomerulonephritis?
- Inflammation of the glomeruli.
- Often post-streptococcal (after a strep infection).
What are the Causes / Risk Factors?
- Post-streptococcal infection
- Autoimmune (lupus)
- IgA nephropathy
What are the Symptoms?
- Hematuria (tea/cola-colored urine)
- Mild proteinuria
- Periorbital edema
- Hypertension
- ↓urine output
- Recent strep infection
How is it Diagnosed?
- Urinalysis (RBC casts, protein)
- ↑ASO titer (post-strep)
- ↑BUN/creatinine
- Renal biopsy
What is the Treatment?
- Treat infection (antibiotics if strep)
- Manage BP; restrict sodium/fluid
- Diuretics
- Monitor renal function; usually supportive
NCLEX TipPost-strep glomerulonephritis: tea-colored urine + edema + HTN a few weeks after a strep throat or skin infection.
Renal Calculi.
RenalWhat is Renal Calculi?
- Kidney stones — crystallized minerals in the urinary tract.
- Most are calcium-based.
What are the Causes / Risk Factors?
- Dehydration
- High calcium / oxalate / purine intake
- Immobility
- Gout, hyperparathyroidism
What are the Symptoms?
- Severe flank pain (renal colic) radiating to groin
- Hematuria
- N/V
- Frequency, urgency
- Diaphoresis, restlessness
How is it Diagnosed?
- CT (non-contrast, definitive)
- Urinalysis (hematuria)
- KUB X-ray, ultrasound
What is the Treatment?
- ↑fluids (2–3 L/day); STRAIN all urine
- Pain control
- Lithotripsy or surgical removal
- Diet based on stone type; prevent recurrence
NCLEX TipStrain all urine to catch the stone for analysis. Push fluids and control the severe colicky pain.
Benign Prostatic Hyperplasia.
Male GUWhat is Benign Prostatic Hyperplasia?
- Non-cancerous enlargement of the prostate.
- Compresses the urethra → obstruction.
What are the Causes / Risk Factors?
- Aging
- Hormonal changes (DHT)
What are the Symptoms?
- Weak stream, hesitancy
- Frequency, urgency, nocturia
- Incomplete emptying, dribbling
- Urinary retention
- Recurrent UTIs
How is it Diagnosed?
- Digital rectal exam (enlarged prostate)
- PSA (rule out cancer)
- Urinalysis, post-void residual
What is the Treatment?
- Alpha blockers (tamsulosin), 5-alpha reductase inhibitors (finasteride)
- Avoid anticholinergics / decongestants (worsen retention)
- TURP (surgery)
- Post-TURP: monitor bleeding, continuous bladder irrigation
NCLEX TipBPH: alpha blockers (tamsulosin) relax the prostate. Avoid anticholinergics and decongestants — they worsen retention.
Dialysis.
ChronicPurpose
- Removes wastes, excess fluid, and toxins when the kidneys fail
- Hemodialysis (AV fistula/catheter) or peritoneal dialysis
AV Fistula Care
- Assess for a thrill (feel) and bruit (hear) — patency
- NO BP, blood draws, or IV in the fistula arm
- Monitor distal circulation
Key Nursing Points
- Hold certain meds (antihypertensives) before hemodialysis
- Weigh before/after (fluid removed)
- Peritoneal: cloudy return = peritonitis (infection)
- Watch for hypotension and disequilibrium syndrome
NCLEX TipProtect the AV fistula: check for a thrill and bruit, and never use that arm for BP, IVs, or blood draws.
Urinary Incontinence.
BladderWhat is Urinary Incontinence?
- Involuntary loss of urine.
- Types: stress, urge, overflow, functional.
What are the Causes / Risk Factors?
- Weak pelvic floor (stress)
- Overactive bladder (urge)
- Retention / obstruction (overflow)
- Immobility / cognition (functional)
What are the Symptoms?
- Stress: leak with cough/sneeze/laugh
- Urge: sudden strong urge
- Overflow: dribbling, incomplete emptying
How is it Diagnosed?
- History, bladder diary
- Post-void residual
- Urinalysis
What is the Treatment?
- Pelvic floor (Kegel) exercises
- Bladder training, scheduled voiding
- Treat cause; anticholinergics (urge)
- Skin care; weight loss; limit caffeine
NCLEX TipStress incontinence responds to Kegel exercises. Urge incontinence responds to bladder training / anticholinergics.
Bladder Cancer.
OncologyWhat is Bladder Cancer?
- Malignancy of the bladder lining.
- Hallmark: painless hematuria.
What are the Causes / Risk Factors?
- Smoking (major)
- Occupational dyes / chemicals
- Chronic bladder irritation
- Older age, male
What are the Symptoms?
- Painless gross hematuria (classic)
- Frequency, urgency, dysuria
- Later: pelvic pain
How is it Diagnosed?
- Cystoscopy with biopsy
- Urine cytology
- CT urogram
What is the Treatment?
- Transurethral resection (TURBT)
- Intravesical chemo / BCG
- Cystectomy + urinary diversion (advanced)
- Smoking cessation; ostomy care if diversion
NCLEX TipPainless hematuria is the classic sign of bladder cancer — always investigate it. Smoking is the biggest risk factor.
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