
Respiratory
NCLEX Clinical Study Booklet · 11 cards
Asthma.
AirwayWhat is Asthma?
- Chronic reversible airway inflammation with bronchospasm.
- Narrowed airways trap air → wheezing and difficulty exhaling.
What are the Causes / Risk Factors?
- Allergens (dust, pollen, dander)
- Respiratory infections
- Cold air, exercise
- Smoke, pollution
- Stress
- Aspirin/NSAIDs (some)
What are the Symptoms?
- Expiratory wheezing
- Dyspnea, chest tightness
- Cough, prolonged expiration
- Accessory muscle use
- Anxiety
- Silent chest = ominous
How is it Diagnosed?
- ↓Peak expiratory flow rate
- Spirometry (reversible obstruction)
- Pulse oximetry, ABG
- History of triggers
What is the Treatment?
- Rescue: short-acting beta agonist (albuterol)
- Controllers: inhaled corticosteroids, LABA
- Avoid triggers
- High Fowler's, O₂; teach inhaler/spacer
NCLEX TipA silent chest with no wheezing during an attack is an emergency — airflow is severely limited.
COPD.
ChronicWhat is COPD?
- Progressive, irreversible airflow limitation (chronic bronchitis + emphysema).
- Air trapping → CO₂ retention.
What are the Causes / Risk Factors?
- Smoking (primary)
- Occupational/pollutant exposure
- Alpha-1 antitrypsin deficiency
- Recurrent infections
What are the Symptoms?
- Chronic productive cough
- Dyspnea, prolonged expiration
- Barrel chest
- Pursed-lip breathing
- Wheezes/crackles
- Clubbing, hypoxia
How is it Diagnosed?
- Spirometry (↓FEV1/FVC)
- ABG: chronic respiratory acidosis
- CXR: hyperinflation
- Pulse oximetry
What is the Treatment?
- Bronchodilators, inhaled corticosteroids
- LOW-flow O₂ (1–2 L)
- Smoking cessation
- Pursed-lip breathing; flu/pneumococcal vaccines
NCLEX TipGive COPD patients LOW-flow oxygen — high O₂ can suppress their hypoxic drive to breathe.
Pneumonia.
InfectionWhat is Pneumonia?
- Infection and inflammation of lung tissue with alveolar consolidation.
- Impairs gas exchange.
What are the Causes / Risk Factors?
- Bacterial (S. pneumoniae), viral, fungal
- Aspiration
- Immobility, immunosuppression
- Older age, smoking
What are the Symptoms?
- Fever, chills
- Productive cough (rusty/purulent sputum)
- Pleuritic chest pain
- Dyspnea, tachypnea
- Crackles, ↓breath sounds
- Confusion (elderly)
How is it Diagnosed?
- CXR (consolidation)
- Sputum culture
- ↑WBC
- Pulse oximetry, ABG
What is the Treatment?
- Antibiotics (bacterial)
- O₂, hydration, rest
- Incentive spirometer, deep breathing, ambulation
- Antipyretics; vaccines
NCLEX TipPush fluids, deep breathing, and early mobility. In the elderly, confusion may be the only sign.
Tuberculosis.
InfectionWhat is Tuberculosis?
- Infection by Mycobacterium tuberculosis, primarily the lungs.
- Airborne; may be latent or active.
What are the Causes / Risk Factors?
- Airborne droplet nuclei (coughing)
- Crowded/close contact
- Immunosuppression (HIV)
- Homelessness, incarceration
What are the Symptoms?
- Productive cough >3 weeks
- Hemoptysis
- Night sweats
- Low-grade fever
- Weight loss, fatigue, anorexia
How is it Diagnosed?
- Positive TST (Mantoux) / IGRA
- Sputum AFB smear & culture (confirms)
- CXR (upper-lobe cavities)
What is the Treatment?
- Airborne precautions (negative-pressure, N95)
- RIPE: Rifampin, Isoniazid, Pyrazinamide, Ethambutol
- Emphasize adherence (DOT)
- Rifampin turns secretions orange
NCLEX TipTB needs airborne precautions and months of combination therapy — adherence prevents drug resistance.
Pulmonary Embolism.
EmergencyWhat is Pulmonary Embolism?
- A clot (usually from a DVT) lodges in the pulmonary artery.
- Blocks pulmonary blood flow — life-threatening.
What are the Causes / Risk Factors?
- DVT (most common source)
- Immobility, recent surgery
- Hypercoagulability
- Fractures (fat embolism), long travel
What are the Symptoms?
- Sudden dyspnea & pleuritic chest pain
- Tachypnea, tachycardia
- Anxiety, restlessness
- Hypoxia, hemoptysis
- Hypotension (massive PE)
How is it Diagnosed?
- CT pulmonary angiography (definitive)
- D-dimer
- ABG (hypoxemia, respiratory alkalosis)
- V/Q scan
What is the Treatment?
- O₂, high Fowler's
- Anticoagulation (heparin → warfarin/DOAC)
- Thrombolytics for massive PE
- Prevent DVT (mobility, prophylaxis)
NCLEX TipSudden dyspnea + chest pain + tachycardia after surgery/immobility = suspect PE. Oxygenate and anticoagulate.
ARDS.
EmergencyWhat is ARDS?
- Acute severe lung injury with non-cardiogenic pulmonary edema.
- Refractory hypoxemia despite oxygen.
What are the Causes / Risk Factors?
- Sepsis (common)
- Aspiration
- Trauma, near-drowning
- Pancreatitis
- Massive transfusion
What are the Symptoms?
- Severe dyspnea, tachypnea
- Refractory hypoxemia (low O₂ despite high FiO₂)
- Crackles
- Restlessness, cyanosis
- Accessory muscle use
How is it Diagnosed?
- ABG: severe hypoxemia
- CXR: bilateral 'white-out' infiltrates
- Rule out cardiac cause (normal PCWP)
What is the Treatment?
- Mechanical ventilation with PEEP
- Low tidal volume; prone positioning
- Treat underlying cause (e.g., sepsis)
- Sedation; monitor hemodynamics
NCLEX TipARDS = refractory hypoxemia (no improvement with O₂) + bilateral infiltrates. Treat with PEEP and the cause.
Pneumothorax.
EmergencyWhat is Pneumothorax?
- Air in the pleural space collapses the lung.
- Tension pneumothorax shifts the mediastinum — emergency.
What are the Causes / Risk Factors?
- Chest trauma / rib fracture
- Central line insertion
- Ruptured bleb (spontaneous)
- Barotrauma (ventilation)
What are the Symptoms?
- Sudden sharp pleuritic chest pain
- Dyspnea
- ↓/absent breath sounds on affected side
- Tracheal deviation (tension — away from side)
- Hypotension, distended neck veins (tension)
How is it Diagnosed?
- CXR (definitive)
- Hyperresonance, absent breath sounds
- Assess for tension (emergency)
What is the Treatment?
- Chest tube with water-seal drainage
- Tension: emergent needle decompression
- O₂, high Fowler's
- Monitor tube & lung re-expansion
NCLEX TipTracheal deviation + hypotension + absent breath sounds = tension pneumothorax → immediate needle decompression.
Pleural Effusion.
ChronicWhat is Pleural Effusion?
- Excess fluid in the pleural space.
- Compresses the lung and impairs expansion.
What are the Causes / Risk Factors?
- Heart failure
- Pneumonia / infection
- Malignancy
- Cirrhosis, nephrotic syndrome
What are the Symptoms?
- Dyspnea
- Pleuritic chest pain
- ↓breath sounds & dullness to percussion
- Decreased chest expansion
- Cough
How is it Diagnosed?
- CXR / ultrasound
- Thoracentesis (diagnostic & therapeutic)
- Fluid analysis (exudate vs transudate)
What is the Treatment?
- Thoracentesis to drain fluid
- Treat underlying cause
- O₂; position for comfort
- Chest tube if large/recurrent
NCLEX TipDullness to percussion with diminished breath sounds at the base suggests effusion; thoracentesis drains it.
Atelectasis.
Post-opWhat is Atelectasis?
- Collapse of alveoli → reduced gas exchange.
- Common after surgery and with immobility.
What are the Causes / Risk Factors?
- Post-op hypoventilation
- Immobility, shallow breathing
- Mucus plugging
- Pain limiting deep breaths
What are the Symptoms?
- Dyspnea, tachypnea
- ↓breath sounds over the area
- Low-grade fever (early post-op)
- Hypoxia, cough
How is it Diagnosed?
- CXR
- Auscultation (diminished sounds)
- Pulse oximetry
What is the Treatment?
- Incentive spirometer
- Deep breathing & coughing, splinting
- Early ambulation
- Adequate pain control; reposition
NCLEX TipAtelectasis is the top cause of fever in the first 24–48h post-op — prevent with incentive spirometry and mobility.
Chest Tube Management.
Post-opPurpose
- Removes air (pneumothorax) or fluid (effusion/hemothorax) from the pleural space
- Restores negative pressure so the lung re-expands
Normal Findings
- Gentle tidaling (fluctuation) in the water-seal chamber
- Gentle bubbling in the suction-control chamber (if on suction)
- Drainage marked and monitored over time
Red Flags & Actions
- Continuous bubbling in water-seal = AIR LEAK
- Sudden bright-red or ↑ drainage = hemorrhage — notify provider
- No tidaling = obstruction OR lung re-expanded
- If it disconnects: place end in sterile water. If it dislodges: sterile dressing taped on 3 sides
NCLEX TipTube disconnects → submerge end in sterile water. Tube dislodges from chest → occlusive dressing taped on 3 sides.
Respiratory Failure.
EmergencyWhat is Respiratory Failure?
- Inadequate gas exchange: hypoxemia (PaO₂ <60) and/or hypercapnia (PaCO₂ >50).
- Type 1 (oxygenation) vs Type 2 (ventilation).
What are the Causes / Risk Factors?
- COPD, asthma, pneumonia, ARDS
- Opioid overdose (hypoventilation)
- Neuromuscular disease
- Pulmonary embolism
What are the Symptoms?
- Dyspnea, tachypnea → later bradypnea
- Restlessness → confusion → ↓LOC
- Cyanosis
- Accessory muscle use
- Tachycardia, dysrhythmias
How is it Diagnosed?
- ABG (hypoxemia / hypercapnia)
- Pulse oximetry
- CXR; identify cause
What is the Treatment?
- O₂ therapy; support airway
- Mechanical ventilation / BiPAP if needed
- Treat underlying cause
- Upright position; monitor closely
NCLEX TipEarly hypoxia shows as restlessness/agitation; cyanosis and bradycardia are late. Act on the early signs.
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